Data & Documentation

MOST has collected both clinical data from case report forms (questionnaires and examinations) and knee joint images from radiographs and MRI. Please use the link to the right (Steps to Obtaining Data and Images) for more information.

Clinical and Endpoints (Outcomes) Assessment

The Dataset Description, Annotated Forms, Variable Guides, and Distributions for Clinical and Endpoints Assessment are available HERE.

 

  • - 84-month Telephone Interview and Clinic Visit
  • - 72-month Telephone Interview
  • - 60-month Telephone Interview and Clinic Visit
  • - 30-month Telephone Interview and Clinic Visit
  • - 15-month Telephone Interview and Clinic Visit
  • - Baseline Telephone Screen and Enrollment Visit
  • - Outcomes (Endpoints)

 

 

​Other Documents

 

Imaging Assessments

The Dataset Description, Annotated Forms, Variable Guide, and Distributions for Longitudinal Radiograph and MR Image Assessments are available HERE.

A) Longitudinal Radiograph Assessments

Semi-quantitative scoring of radiographs, including Kellgren and Lawrence grades, OARSI joint space narrowing, osteophyte grades, and features of patello-femoral OA

 

  • - Baseline to 84-month Longitudinal Knee Radiograph Assessments (PA, Lateral, and Full-limb (Hip-Knee-Ankle) Mechanical Alignment) (V01235XRAY)

Note: As of April 2016, the V012XRAY and V0123XRAY datasets are no longer available. The data have been updated and are now available in the Longitudinal Baseline to 84 Longitudinal Knee Radiograph Assessments dataset (V01235XRAY).

 

B) Longitudinal MR Image Assessments

Semi-quantitative Whole-Organ Magnetic Resonance Imaging (WORMS) scoring for presence and severity of structural features related to OA, including cartilage lesions, meniscal damage, bone marrow lesions, and osteophytes.

 

  • - Baseline, 60-month, 84-month MRI Assessment (V035WORMS)
  • - Baseline to 30-month Incident Radiographic OA (V02WORMS_INCIDENTROA)
  • - Baseline to 30-month Subset of Knees with Baseline OA (V02WORMS_BLROA)
  • - Baseline to 15-month Incident Knee Symptoms Cases and Controls (V01WORMS)

 

Knee Radiograph and MR Imaging

To obtain data and images, complete the Data Use Agreement and the Request for MOST Research Dataset Form. See Steps to Obtaining Data and Images. Email your signed Data Use Agreement and the Request for MOST Research Dataset to [email protected].

A) Radiographs Available

 

  • - Bilateral PA fixed flexion knee radiographs
  • - Unilateral left and right knee lateral view radiographs
  • - Full-limb radiographs

 

For details about the acquisition protocols, see the MOST Knee and Full Limb Radiography Operations Manual available HERE.

 

B) MR Images Available

 

  • - Axial, sagittal and coronal MRI images are available for each knee scanned

 

For details about the acquisition protocols, see the MOST 1.0T MRI Operations Manual available HERE.